No, when the NA460C storage is connected to a Thunderbolt 2 computer via the TB2-to-TB3 adapter, the computer won’t work with the NA460C because computer’s Thunderbolt 2 port doesn’t support the USB protocol. However, normally the TB2 computer/laptop will also provide at least one USB Type-A port, so you can just connect your NA460C storage to computer/laptop's USB Type-A port via the USB-C to USB-A data cable in support of work.

On the other hand, as the NA460C storage is connected directly to a Thunderbolt 3 computer/laptop's TB3 port via the supplied USB 3.1 USB-C to USB-C data cable, the TB3 computer can work with the NA460C due to computer/laptop’s Thunderbolt 3 port supporting the USB protocol natively.